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Proton pump inhibitors interfere with Clopidogrel

The anti-clotting action of the medication Clopidogrel ( Plavix ) can be compromised by common drugs for the treatment of heartburn and ulcers resulting in a roughly 50% increase in the combined risk of hospitalization for heart attack, stroke and other serious cardiovascular illnesses, according to...
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Gastroesophageal reflux disease: FDA has approved Nexium for use in children ages 1-11 years

The FDA ( Food and Drug Administration ) has approved Nexium ( Esomeprazole ) for short-term use in children ages 1-11 years for the treatment of gastroesophageal reflux disease ( GERD ). The agency approved Nexium in two forms, a delayed-release capsule and liquid form. Nexium is approved in 10 ...
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Long-term proton pump inhibitor therapy linked to risk of hip fracture

Proton pump inhibitors ( PPIs ) are used for the treatment of acid-related diseases such as gastro esophageal reflux disease ( GERD ). A study found that proton pump inhibitors are associated with a greater risk of hip fracture. Some research has shown that PPI therapy may decrease insoluble cal...
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Seeking to prevent cancer using anti-inflammatory medications

Mayo Clinic Cancer Center has begun three clinical studies looking at the use of nonsteroidal anti-inflammatory drugs ( NSAIDs ) to prevent cancer ( colon, esophageal or lung ). These studies are part of the ongoing Cancer Center chemoprevention program, using medications to prevent cancer, especial...
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Zollinger-Ellison syndrome: Esomeprazole maintains normal acid production

A study has shown that the proton pump inhibitor Esomeprazole ( Nexium ) maintains normal gastric acid levels in patients with Zollinger-Ellison syndrome or idiopathic gastric acid hypersecretion. Twenty-one patients received one of several doses of Esomeprazole, depending on the degree of their ...
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Esomeprazole more effective than Lansoprazole in maintaining healing of erosive esophagitis

A new study, involving more than 1,000 patients with healed erosive esophagitis, has shown that Esomeprazole ( Nexium ) is more effective than Lansoprazole ( Prevacid ) in preventing a recurrence and is equally effective in reducing its associated symptoms. Esomeprazole and Lansoprazole are proton ...
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H2 blockers linked to life threatening bowel infection in premature infants

Researchers in an NIH ( National Institutes of Health ) network have found that premature infants given drugs used to treat acid reflux are slightly more likely to develop a potentially fatal bowel disorder than are infants who are not treated with these drugs. The drugs, known as H2 blockers, i...
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Genetic profile of eosinophilic esophagitis discovered

A disease that was often misdiagnosed in the past, eosinophilic esophagitis has been increasingly recognized in the United States, Europe, Canada and Japan in the last few years. Cases of the disease can be devastating since children who suffer from it may have a host of lifelong problems. Now,...
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Lexiva for the treatment of HIV infection in adults in combination with other antiretroviral medications

The FDA ( U.S. Food and Drug Administration ) approved an application to add clinical data to the prescribing information for Lexiva ( Fosamprenavir calcium ), an HIV protease inhibitor ( PI ). The newly added information shows that simultaneous administration of Lexiva in combination with Esomepra...
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Anti-inflammatory drugs may cut risk of esophageal cancer in people with Barrett's esophagus

Aspirin and other nonsteroidal anti-inflammatory drugs ( NSAIDs ), such as Ibuprofen, may significantly reduce the risk of esophageal cancer among people with Barrett's esophagus, a precancerous condition associated with chronic heartburn that affects an estimated 1 million to 2 million Americans. ...
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