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Age-related cataract
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Serious ocular adverse reactions linked to intravitreal injection of Triamcinolone acetonide
Triamcinolone acetonide is a synthetic corticosteroid primarily used for its marked anti-inflammatory action. In Canada, the 40-mg/mL suspension has been authorized for intramuscular and intra-articular administration or for injection into tendon sheaths or ganglia. It is indicated for systemic cor...
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Antioxidants may help to protect patients with retinitis pigmentosa
Researchers at Johns Hopkins have successfully blocked the advance of retinal degeneration in mice with a form of retinitis pigmentosa by treating them with Vitamin E, alpha-Lipoic acid and other antioxidant chemicals. " Much more work needs to be done to determine if what we did in mice will wor...
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Statin use linked to reduced risk of nuclear cataract
The statins are associated with a lower incidence of nuclear cataract, the most common type of age-related cataract. Statins are widely used to decrease serum cholesterol for cardiovascular disease prevention. Statins have also been shown to have antioxidant activity. Oxidative stress ( a condi...
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Wet age-related macular degeneration: FDA has approved Lucentis
The FDA ( Food and Drug Administration ) has approved Lucentis ( Ranibizumab injection ) for the treatment of patients with neovascular (wet) age-related macular degeneration ( AMD ). Age-related macular degeneration, a retinal disease causing severe and irreversible vision loss, is a major cause...
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Wet age-related macular degeneration: FDA has approved Lucentis
The FDA ( Food and Drug Administration ) has approved Lucentis ( Ranibizumab ) for the treatment of patients with neovascular ( wet ) age-related macular degeneration ( AMD ). The FDA approval of Lucentis is based on data from two large Phase III clinical trials ( MARINA and ANCHOR ). In these s...
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Macugen in treatment of diabetic macular edema
Imaging data from a Phase 2 study of Pegaptanib ( Macugen ) in diabetic macular edema ( DME ) showed a reversal of capillary microaneurysms, retinal ischemia and neovascularization -- all important signs of diabetic retinopathy. Macugen is indicated in the United States for the treatment of n...
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