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American Association for Cancer Research
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Dutasteride reduces risk of prostate carcinoma diagnosis in high-risk men
Dutasteride ( Avodart ) has shown to reduce the risk of a prostate cancer diagnosis by 23 percent in men with an increased risk of the disease. The results are reported in the New England Journal of Medicine ( NEJM ). The four-year study found that Dutasteride significantly reduced the chances t...
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Postmenopausal breast cancer: role of bisphosphonates
Bisphosphonates are routinely given to women with postmenopausal breast cancer, but new data suggests that these agents may play a role in reducing recurrent breast cancer as well. The effect of Zoledronic acid on aromatase inhibitor-associated bone loss in postmenopausal women with early breast...
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Chronic periodontitis is an independent risk factor for head and neck squamous cell carcinoma
Chronic periodontitis, a form of gum disease, is an independent risk factor for head and neck squamous cell carcinoma. This suggests the need for increased efforts to prevent and treat periodontitis as a possible means to reduce the risk of this form of cancer. Results of this study are publishe...
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Acetylsalicylic acid use after colorectal tumor diagnosis associated with improved survival
Men and women with colorectal cancer and began regular use of Acetylsalicylic acid ( Aspirin ) had a lower risk of overall and colorectal cancer death compared to patients not using Acetylsalicylic acid. Numerous prospective, observational studies demonstrate that regular Acetylsalicylic acid use...
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Inoperable hepatocellular carcinoma: Lapatinib shows minimal effect
Use of Lapatinib ( Tykerb ) to delay tumor growth and improve the survival of patients with inoperable hepatocellular carcinoma, or liver cancer, only benefited certain subgroups of patients. While results of this study were largely negative, patients that exhibited toxicity from the drug in the for...
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CT imaging may predict survival in patients with metastatic colorectal cancer treated with Bevacizumab
Using routine computed tomography ( CT ) imaging to analyze form and structural changes to colorectal liver metastasis after Bevacizumab ( Avastin ) and chemotherapy may predict overall survival. The findings are published in the Journal of American Medical Association. When combined with chemot...
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Breast cancer: management and prognosis
As therapies for breast cancer continue to emerge, the issues of how to best monitor success and gauge prognosis remain important questions. The following abstracts have been presented at the CTRC-AACR Annual San Antonio Breast Cancer Symposium. Results of chemotherapy alone, with sequential or ...
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Type II diabetes: pancreatic cancer risk decreased by Metformin, increased by Insulin or insulin secretagogues
The antidiabetic medication Metformin is associated with a reduced risk of pancreatic cancer in diabetics, according to a new study in Gastroenterology. However, other commonly used therapies, such as Insulin or insulin secretagogues, may be associated with increased risk of tumor. Researchers a...
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Cancer: new biomarkers can predict response to treatments
Genetic variations ensure that no two people are exactly alike, nor are their cancers. Researchers now have the tools and the knowledge to predict how individuals will respond to cancer therapy, enabling more precise and effective treatment. At the 2008 Annual Meeting of the American Association ...
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Men who take Acetylsalicylic acid have significantly lower PSA levels
The use of Acetylsalicylic acid ( Aspirin ) and other non-steroidal anti-inflammatory drugs ( NSAIDs ) is significantly associated with lower PSA levels, especially among men with prostate cancer, say researchers at Vanderbilt University. This large analysis known as the Nashville Men's Health St...
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