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American Journal of Psychiatry

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Citalopram, an antidepressant, has shown early promise in treating agitation and psychotic symptoms of dementia
Researchers have found surprising evidence that an antidepressant, Citalopram, may perform as well as a commonly-prescribed antipsychotic, Risperidone, in the alleviation of severe agitation and psychotic symptoms of dementia. Researchers also found that the antidepressant was associated with signif...
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Aripiprazole reverses Haloperidol-induced hyperprolactinemia
Hyperprolactinemia and associated side effects often occur with antipsychotics. Researchers at Inje University, Republic of Korea, investigated the effect of adjunctive treatment with Aripiprazole ( Abilify ) on hyperprolactinemia and psychopathology in patients with schizophrenia maintained wit...
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Zonisamide improves tremors, involuntary movements in Parkinson patients
A study, published in the journal Neurology, found that a drug used to treat epilepsy has been found to significantly improve tremors, motor fluctuations, and other involuntary movements, or dyskinesias, in patients with Parkinson disease. The three-month, multi-center study in Japan involved 27...
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Metformin stabilizes weight in paediatric patients treated with atypical antipsychotics
Atypical antipsychotics have benefits for psychiatric illness in children and adolescents but are often accompanied by significant weight gain, possibly resulting in type 2 diabetes. Metformin ( Glucophage ) is a medication used to regulate blood glucose in type 2 diabetes. A 16-week double-b...
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Psychosis: Clozapine linked to metabolic syndrome
Patients who take Clozapine ( Clozaril ), the most effective antipsychotic drug, have significantly higher rates of metabolic syndrome, according to a first-of-a-kind study by researchers from University of Rochester Medical Center. Metabolic syndrome is a group of conditions that increase the r...
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Onset of psychosis may be delayed by Olanzapine
A study, published in The American Journal of Psychiatry, has shown that for young people who clearly seem to be developing early signs of schizophrenia, treatment with the antipsychotic drug Olanzapine ( Zyprexa ) appears to lower or delay the rate of conversion to full-blown psychosis. The find...
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Depression: brain imaging can predict effectiveness of cognitive behavior therapy
Brain imaging can predict whether or not cognitive behavior therapy ( CBT ) will help a patient recover from depression, according to researchers at University of Pittsburgh School of Medicine. The research is published in the American Journal of Psychiatry. More than 17 million adults in the ...
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Antidepressants potentially misused in treating adolescents
A research from the Stanford University School of Medicine provides critical documentation of the potential misuse of the antidepressants in young patients in the years leading up to the FDA's decision to issue the so-called "black-box" warnings. The researchers found that, despite clinical guide...
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Depression: initial results help determine successful treatments
A trial for depression has helped clinicians to track "real world" patients who became symptom-free and to identify those who were resistant to the initial treatment. Participants treated in both medical and specialty mental health care settings experienced a remission of symptoms in 12 to 14 we...
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Prevalence of night eating syndrome among people with psychiatric conditions
Researchers at the University of Pennsylvania School of Medicine and the University of Minnesota found that night eating syndrome is a common disorder among psychiatric outpatients and is associated with substance use and obesity. The study is published in the The American Journal of Psychiatry. ...
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