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Dutasteride reduces risk of prostate carcinoma diagnosis in high-risk men

Dutasteride ( Avodart ) has shown to reduce the risk of a prostate cancer diagnosis by 23 percent in men with an increased risk of the disease. The results are reported in the New England Journal of Medicine ( NEJM ). The four-year study found that Dutasteride significantly reduced the chances t...
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Low-risk patients undergoing elective PCI: platelet function tests may provide modest benefit in predicting cardiac outcomes

An analysis of six tests that are used to measure platelet function and help gauge the effectiveness of antiplatelet drugs for patients undergoing a cardiac procedure such as a coronary stent implantation found that only three of the tests were associated with a modest ability to predict outcomes su...
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Pediatric patients: use of antipsychotics associated with significant weight gain

Many pediatric and adolescent patients who received second-generation antipsychotic medications experienced significant weight gain, along with varied adverse effects on cholesterol and triglyceride levels and other metabolic measures. Treatment for psychotic disorders, bipolar disorder, and nonp...
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Postmenopausal breast cancer: role of bisphosphonates

Bisphosphonates are routinely given to women with postmenopausal breast cancer, but new data suggests that these agents may play a role in reducing recurrent breast cancer as well. The effect of Zoledronic acid on aromatase inhibitor-associated bone loss in postmenopausal women with early breast...
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Chronic periodontitis is an independent risk factor for head and neck squamous cell carcinoma

Chronic periodontitis, a form of gum disease, is an independent risk factor for head and neck squamous cell carcinoma. This suggests the need for increased efforts to prevent and treat periodontitis as a possible means to reduce the risk of this form of cancer. Results of this study are publishe...
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Acetylsalicylic acid use after colorectal tumor diagnosis associated with improved survival

Men and women with colorectal cancer and began regular use of Acetylsalicylic acid ( Aspirin ) had a lower risk of overall and colorectal cancer death compared to patients not using Acetylsalicylic acid. Numerous prospective, observational studies demonstrate that regular Acetylsalicylic acid use...
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Inoperable hepatocellular carcinoma: Lapatinib shows minimal effect

Use of Lapatinib ( Tykerb ) to delay tumor growth and improve the survival of patients with inoperable hepatocellular carcinoma, or liver cancer, only benefited certain subgroups of patients. While results of this study were largely negative, patients that exhibited toxicity from the drug in the for...
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CT imaging may predict survival in patients with metastatic colorectal cancer treated with Bevacizumab

Using routine computed tomography ( CT ) imaging to analyze form and structural changes to colorectal liver metastasis after Bevacizumab ( Avastin ) and chemotherapy may predict overall survival. The findings are published in the Journal of American Medical Association. When combined with chemot...
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Rituximab reduces inflammation in patients with lupus nephritis

Treatment with Rituximab can significantly benefit some patients with severe lupus nephritis who do not respond to conventional therapy, according to a study published in the Clinical Journal of the American Society Nephrology ( CJASN ). The findings indicate that this immunosuppressive agent could ...
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Breast cancer: management and prognosis

As therapies for breast cancer continue to emerge, the issues of how to best monitor success and gauge prognosis remain important questions. The following abstracts have been presented at the CTRC-AACR Annual San Antonio Breast Cancer Symposium. Results of chemotherapy alone, with sequential or ...
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