MedicineNews.net - Medical Updates

Pfizer-BioNTech COVID-19 vaccine: CDC Report on December 23, 2020

As of December 23, 2020, a reported 1,893,360 first doses of Pfizer-BioNTech COVID-19 vaccine had been administered in the United States, and reports of 4,393 ( 0.2% ) adverse events after receipt of ... read article

FDA: four-week dosing approved in all Imfinzi indications, reducing medical visits and improving patient convenience

Imfinzi ( Durvalumab ) has been approved in the US for an additional dosing option, a 1,500 mg fixed dose every four weeks, in the approved indications of unresectable stage III non-small cell lung ca ... read article

Xalkori for the treatment of pediatric ALK-positive anaplastic large cell lymphoma: FDA has accepted supplemental new drug application

The FDA ( U.S. Food and Drug Administration ) has accepted and granted priority review to the supplemental New Drug Application( sNDA ) for Crizotinib ( Xalkori ) for the treatment of pediatric patien ... read article

DMC Committee has recommended continuation without changes of phase 3 clinical trial of Omecamtiv Mecarbil in patients with heart failure

The second and final planned interim analysis of the GALACTIC-HF trial, which has included consideration of pre-specified criteria for futility and superiority, was completed. The DMC ( Data Monitori ... read article

FDA on use of non-steroidal anti-inflammatory drugs for COVID-19

FDA ( Food and Drug Administration ) is aware of news reports stating the use of non-steroidal anti-inflammatory drugs ( NSAIDs ), such as Ibuprofen, could worsen coronavirus disease ( COVID-19 ). T ... read article

Muscle-invasive urothelial cancer: Atezolizumab as adjuvant monotherapy treatment did not meet its primary endpoint in IMvigor010

The phase III IMvigor010 study evaluating Atezolizumab ( Tecentriq ) as an adjuvant ( after surgery ) monotherapy treatment did not meet its primary endpoint of disease-free survival ( DFS ) compared ... read article

Safety of sodium-glucose co-transporter 2 inhibitors

Sodium-glucose co-transporter 2 ( SGLT2 ) inhibitors have a well-defined safety profile based on data obtained from numerous clinical trials, including cardiovascular outcomes trials ( CVOTs ) and pos ... read article

Consensus on Testosterone treatment for postmenopausal women with hypoactive sexual desire dysfunction

The Endocrine Society and 10 other internationally esteemed medical societies have issued the first Global Position Statement on the use of Testosterone in the treatment of women. It follows years ... read article

Treatment of hypertension induced albuminuria

Albuminuria is a renal disease that is found to be independently associated with cardiovascular and renal problems without any links to diabetes. In latest ESC/ESH guidelines, microalbuminuria has ... read article

Fluoroquinolones associated with cardiovascular risk

Several fluoroquinolone antibiotics have been associated with cardiac adverse effects, leading to the withdrawal of some of these agents from the market. Cardiac side effects such as QT prolongation ... read article

Anti-HIV drug combination does not increase preterm birth risk

A drug combination aimed at preventing transmission of HIV from a pregnant woman to her fetus likely does not increase the risk for preterm birth and early infant death, according to a re-analysis of ... read article

Pan-cancer analysis of nearly 2,600 gynecologic and breast tumors has revealed five previously unknown subtypes

Researchers from The University of Texas MD Anderson Cancer Center have found a startling amount of new information about molecular features of tumors as well as identified previously unknown cancer s ... read article

Efficacy of cinnamon in patients with type II diabetes mellitus

Multiple studies have evaluated the hypoglycemic effect of cinnamon in patients with diabetes mellitus type II, with conflicting results. Differences in baseline body mass index ( BMI ) of patient ... read article

Learning curve and established phase for uniportal VATS lobectomies: the Papworth experience

Uniportal video-assisted thoracoscopy ( VATS ) has increasingly gained importance in the thoracic surgery scenario. The use of this technique can reduce postoperative pain and length of stay and gives ... read article

Concussion in teenagers increases the risk of multiple sclerosis in later life

Concussion in teenagers increases the risk of multiple sclerosis in later life. However, there is no association with multiple sclerosis for concussion in younger children. The results have demonstr ... read article