MedicineNews.net - Medical Updates

Muscle-invasive urothelial cancer: Atezolizumab as adjuvant monotherapy treatment did not meet its primary endpoint in IMvigor010

The phase III IMvigor010 study evaluating Atezolizumab ( Tecentriq ) as an adjuvant ( after surgery ) monotherapy treatment did not meet its primary endpoint of disease-free survival ( DFS ) compared ... read article

Safety of sodium-glucose co-transporter 2 inhibitors

Sodium-glucose co-transporter 2 ( SGLT2 ) inhibitors have a well-defined safety profile based on data obtained from numerous clinical trials, including cardiovascular outcomes trials ( CVOTs ) and pos ... read article

Consensus on Testosterone treatment for postmenopausal women with hypoactive sexual desire dysfunction

The Endocrine Society and 10 other internationally esteemed medical societies have issued the first Global Position Statement on the use of Testosterone in the treatment of women. It follows years ... read article

Treatment of hypertension induced albuminuria

Albuminuria is a renal disease that is found to be independently associated with cardiovascular and renal problems without any links to diabetes. In latest ESC/ESH guidelines, microalbuminuria has ... read article

Fluoroquinolones associated with cardiovascular risk

Several fluoroquinolone antibiotics have been associated with cardiac adverse effects, leading to the withdrawal of some of these agents from the market. Cardiac side effects such as QT prolongation ... read article

Anti-HIV drug combination does not increase preterm birth risk

A drug combination aimed at preventing transmission of HIV from a pregnant woman to her fetus likely does not increase the risk for preterm birth and early infant death, according to a re-analysis of ... read article

Pan-cancer analysis of nearly 2,600 gynecologic and breast tumors has revealed five previously unknown subtypes

Researchers from The University of Texas MD Anderson Cancer Center have found a startling amount of new information about molecular features of tumors as well as identified previously unknown cancer s ... read article

Efficacy of cinnamon in patients with type II diabetes mellitus

Multiple studies have evaluated the hypoglycemic effect of cinnamon in patients with diabetes mellitus type II, with conflicting results. Differences in baseline body mass index ( BMI ) of patient ... read article

Learning curve and established phase for uniportal VATS lobectomies: the Papworth experience

Uniportal video-assisted thoracoscopy ( VATS ) has increasingly gained importance in the thoracic surgery scenario. The use of this technique can reduce postoperative pain and length of stay and gives ... read article

Concussion in teenagers increases the risk of multiple sclerosis in later life

Concussion in teenagers increases the risk of multiple sclerosis in later life. However, there is no association with multiple sclerosis for concussion in younger children. The results have demonstr ... read article

Breast cancer may be more aggressive in patients with obesity

Women with obesity are more likely to get breast cancer, and a number of studies have provided a reasonable explanation why: after menopause, fat tissue manufactures estrogen, and the estrogen then pr ... read article

P/LAIV, a pandemic influenza vaccine has received positive CHMP opinion

The Committee for Medicinal Products for Human Use ( CHMP ) of the European Medicines Agency ( EMA ) has issued a positive opinion recommending the conditional approval of Pandemic Live Attenuated Inf ... read article

ANGPTL4 inhibition associated with reduced risk of coronary artery disease

The New England Journal of Medicine ( NEJM ) has published a paper showing that inactivating mutations of the angiopoeitin-like 4 ( ANGPTL4 ) gene are associated with a significantly reduced risk of c ... read article

The effect of Tinzaparin, a low-molecular-weight heparin, on the treatment of blood clots in cancer patients

The largest completed study to date on treatments to reduce recurrence of blood clots in cancer patients, has now been published in JAMA. The study has shown that Tinzaparin ( Innohep ) has lowered ... read article

Symptoms of insomnia in psoriasis are directly mediated by pruritus and pain

Psoriasis is an immune-mediated chronic inflammatory disorder which manifests as dermatologic lesions, and psoriatic arthritis in about 30% of cases. Psoriasis is associated with multiple comorbid ... read article