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Pan-cancer analysis of nearly 2,600 gynecologic and breast tumors has revealed five previously unknown subtypes

Researchers from The University of Texas MD Anderson Cancer Center have found a startling amount of new information about molecular features of tumors as well as identified previously unknown cancer s ... read article

Efficacy of cinnamon in patients with type II diabetes mellitus

Multiple studies have evaluated the hypoglycemic effect of cinnamon in patients with diabetes mellitus type II, with conflicting results. Differences in baseline body mass index ( BMI ) of patient ... read article

Learning curve and established phase for uniportal VATS lobectomies: the Papworth experience

Uniportal video-assisted thoracoscopy ( VATS ) has increasingly gained importance in the thoracic surgery scenario. The use of this technique can reduce postoperative pain and length of stay and gives ... read article

Concussion in teenagers increases the risk of multiple sclerosis in later life

Concussion in teenagers increases the risk of multiple sclerosis in later life. However, there is no association with multiple sclerosis for concussion in younger children. The results have demonstr ... read article

Breast cancer may be more aggressive in patients with obesity

Women with obesity are more likely to get breast cancer, and a number of studies have provided a reasonable explanation why: after menopause, fat tissue manufactures estrogen, and the estrogen then pr ... read article

P/LAIV, a pandemic influenza vaccine has received positive CHMP opinion

The Committee for Medicinal Products for Human Use ( CHMP ) of the European Medicines Agency ( EMA ) has issued a positive opinion recommending the conditional approval of Pandemic Live Attenuated Inf ... read article

ANGPTL4 inhibition associated with reduced risk of coronary artery disease

The New England Journal of Medicine ( NEJM ) has published a paper showing that inactivating mutations of the angiopoeitin-like 4 ( ANGPTL4 ) gene are associated with a significantly reduced risk of c ... read article

Symptoms of insomnia in psoriasis are directly mediated by pruritus and pain

Psoriasis is an immune-mediated chronic inflammatory disorder which manifests as dermatologic lesions, and psoriatic arthritis in about 30% of cases. Psoriasis is associated with multiple comorbid ... read article

High-normal blood pressure in young adults linked to risk of heart failure in later life

Mild elevations in blood pressure considered to be in the upper range of normal during young adulthood can lead to subclinical heart damage by middle age, a condition that sets the stage for full-blow ... read article

Smog may be associated to heart disease only in patients with previously diagnosed coronary artery disease

Analyzing more than 16,000 myocardial infarctions that were treated in the Salt Lake City area of Utah ( U.S.A ) from 1993 to 2014, researchers found a significant association between days that had po ... read article

Multiple sclerosis: chemokine receptor CCR2, a key protein involved in a super-inflammatory immune response

Published in the journal Nature Communications, the researchers at the University of Adelaide have identified a key protein involved in a super-inflammatory immune response that drives the progression ... read article

Risk of sudden cardiac death associated with chronic obstructive pulmonary disease

People suffering COPD ( chronic obstructive pulmonary ) disease have an increased risk of sudden cardiac death ( SCD ), according to new research published online in the European Heart Journal. Wh ... read article

Response to statins influenced by genetic variants

A large analysis of over 40,000 individuals undergoing statin treatment has revealed two new genetic variants that may affect how low density lipoprotein ( LDL ) cholesterol responds to statin therapy ... read article

Non-small cell lung cancer: Afatinib provides more than one year additional survival in patients with the most common type of EGFR mutation ( del19 ) compared to chemotherapy

Boehringer Ingelheim has announced results of the pre-specified individual, as well as the exploratory combined, analyses of two phase III trials ( LUX-Lung 3 and LUX-Lung 6 ). These data have demonst ... read article

Higher urine Bisphenol A levels linked to continuous handling of receipts printed on thermal paper

Study participants who handled receipts printed on thermal paper continuously for 2 hours without gloves had an increase in urine Bisphenol A ( BPA ) concentrations compared to when they wore gloves. ... read article